Our Team

Biostatistics Shared Resoure

Motivation: Too many spreadsheets!

An example: START

Very quick tour

Data Input

• Input data ~ multiple formats: Special input formats
• Interface with other software? Export special formats

Data Exploration: Interactive

Clinical Trials Methods

Bayesian Adaptive Design

$\to$ An Adaptive Bayesian Sequential Design for Determining the Subject-Specific Optimal Treatment Length (manuscript in progress)

https://bayesiantrial.shinyapps.io/Bayesian12/

BSR: Yiyi Chen, PhD; Lina Gao, PhD
OHSU: Zunqiu Chen, MS; Matthew F Halsey, PhD; Jodi Lapidus, PhD

• Select directions and weights of various outcomes
• Determine potential length of treatment to be evaluated
• Upload data
• Potential actions: Escalate; De-escalate; Stay

General App & Trial Specific

Present QA plots up front

Provide Instructions!

Old fasioned debugging/logging works

Conclusions

• R Shiny can be a tool to creatively interact with data
• Improve collaboration and promote your methods
• Avoid repetitive analyses and visualizations
• Instructions, data checks/QA are vital

START

• working on extensions to single-cell and proteomics specific analyses and visualizations
• (one day) switch to use modules
• we welcome collaboration!

Thank you!

Contact me: minnier-[at]-ohsu.edu, datapointier, jminnier

START: http://jessicaminnier.com/STARTapp/

RELATED SLIDES ON SHINY (Challenges/Responsibilities):

• Data Day Texas http://bit.ly/shiny-ddtx
• CSP: http://bit.ly/shiny-csp18

Slides available at http://bit.ly/rpharma-minnier

Code for slides available at https://github.com/jminnier/talks_etc

Slides created via the R package xaringan by Yihui Xie with the metropolis theme